A simple and reproducible measure of adipose depots with non-contrast post-mortem computed tomography
نویسندگان
چکیده
Abstract Background and aim Obesity is associated with an increase in different adipose depots. The anatomic distribution of internal confers risks. Recently, significant interest has emerged the expansion epicardial tissue (EAT) as a mediator adverse cardiovascular events. Often, post-mortem examination remains best method investigating morphological changes health disease. This study aimed to develop simple, reproducible, non-invasive protocol for measurement adiposity using computed tomography (PMCT). Patients methods 101 consecutive subjects underwent non-contrast scans. Measurements were performed open-source software 3D Slicer by non-expert researcher. An expert radiologist cardiologist verified abdominal cardiac sites adiposity, respectively. We measure total EAT, sub-depots extra-pericardial adipose, visceral subcutaneous suprasternal adipose. Results found excellent reproducibility our measures anterior right atrial tissue, intraclass correlations between 0.82 0.99 each measure. Due lack suitable anatomical boundaries, other including interventricular groove, not reproducible. Conclusions Quantification EAT are readily reproducible on CT. They can be reliably measured researchers small amount training, therefore used investigate
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ژورنال
عنوان ژورنال: Imaging
سال: 2022
ISSN: ['2732-0960']
DOI: https://doi.org/10.1556/1647.2022.00066